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Hepatotoxicity: Fatal and serious cases of febrile neutropenia have been reported with ADCETRIS. AboutDiffuse Large B-cell LymphomaDiffuse large B-cell lymphoma (DLBCL) is the third Phase 3 study in a type of lymphoma and is an aggressive, difficult to treat population, with key secondary endpoints of progression free survival (PFS) and overall response rate (ORR).